- haohan药用辅料三氯叔丁醇中丙酮和三lv甲烷测定毛细管柱PEG-20M
详细信息
品牌:haohan 型号:PEG-20M 加工定制:是 规格:30M*0.32MM*0.5UM 长度:3000 内径:0.32 膜厚:2.0 30M*0.32MM*0.5UM:毛细管柱 药用辅料:三氯叔丁醇 丙酮:三氯、lv甲烷 苯系物:分子筛 3%Dexil-300/Chromosorb W AW D:非甲烷总烃
浩瀚色谱(山东)应用技术开发有限公司,建立三氯叔丁醇有关物质测定的气相色谱分析法,对该辅料质量标准进行修订.方法:以聚乙二醇(PEG-20M)为固定液的毛细管柱.检测器分别为FID(丙酮)和ECD(三氯甲烷);丙酮和三氯甲烷分别在0.5~45μg·mL^(-1)和5~510 ng·mL^(-1)范围内峰面积与浓度呈良好的线性关系(r值分别为0.9997和0.9995);丙酮和三氯甲烷平均回收率分别为95.9%.和107.9%,均符合方法学研究要求;建立方法可增订入中国药典质量标准,用于三氯叔丁醇质量控制.
名称:毛细管柱
规格:30m*0.32mm*0.25um
型号;PEG-20M
应用:三氯叔丁醇药用辅料中丙酮及三lv甲烷的测定
适用于:
安捷伦490在线/便携,4890,5890,6890,7820,7890,8860,8890
岛津GC-14C,GC-2010,GC-2014,GC-2030
赛默飞1310,1300,1610,1600
瓦里安3800系列
布鲁克PE580,590,680,690
磐诺A90,福立GC9790,华爱,天瑞,天美,GC7900,川仪,北分瑞利,东西电子,鲁南瑞虹,捷岛/科晓
Trichlorotert butanol, as an alcohol antibacterial agent, has the ability to coagulate bacterial proteins and globulin. The initial dosage form used for ophthalmic or injectable administration is generally at a concentration of 0.5% (W/V). It is commonly used as an antibacterial agent in adrenaline solutions, posterior pituitary extract, and ophthalmic preparations for the treatment of pupil constriction.
Haohan Chromatography (Shandong) Application Technology Development Co., Ltd. has established a gas chromatography analysis method for the determination of related substances in trichlorotert butanol and revised the quality standards for this excipient Method: A capillary column with polyethylene glycol (PEG-20M) as the stationary phase The detectors are FID (acetone) and ECD (chloroform), respectively; Acetone and trichloromethane showed a good linear relationship between peak area and concentration in the ranges of 0.5-45 μ g · mL ^ (-1) and 5-510 ng · mL ^ (-1), respectively (r values of 0.9997 and 0.9995, respectively); The average recovery rates of acetone and trichloromethane were 95.9% And 107.9%, both meet the requirements of methodological research; The establishment method can be added to the quality standards of the Chinese Pharmacopoeia for the quality control of trichlorotert butanol
Name: Capillary Column
Specification: 30m * 0.32mm * 0.25um
model; PEG-20M
Application: Determination of Acetone and Trilv Methane in Trichlorotert butanol Medicinal Excipients
Applicable to:
Agilent 490 online/portable, 48905890689088608890
Shimadzu GC-14C, GC-2010,GC-2014,GC-2030
Thermo Fisher Scientific 1310130016101600
Varian 3800 Series
Brooke PE580590680690
Panno A90, Fuli GC9790, Huaai, Tianrui, Tianmei, GC7900, Chuanyi, Beifen Ruili, Dongxi Electronics, Lunan Ruihong, Jiedao/Kexiao
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