安捷伦7820A医yong口罩及yi用防护服中环氧乙烷的测定玻璃柱Chromosorb 101 HP 60～80Chromosorb 101 HP 60～80

新型冠状肺炎疫情期间,为加快口罩上市,缩短环氧乙烷的解析时间.方法 随机选取10批次按正常灭菌浓度经环氧乙烷灭菌而未进行任何解析处理的外科口罩为样本,以气相色谱仪作为检测手段,拆掉样本包装,将样品置超净工作台,在垂直流*大风速情况下,检测不同解析时间环氧乙烷的残留量,对检测结果进行分析.结果 与结论通过加大环境空气的流通速度,可使口罩含有的环氧乙烷快速解析,达到标准要求,以合理规避无菌试验前的解析时间,缩短出厂检验周期,加快口罩的上市.

浩瀚色谱（山东）应用技术开发有限公司建立顶空-气相色谱法测定yi用口罩和防护服中环氧乙烷残留量的分析方法。通过实验优化了测定方法和条件,确定了色谱柱类型、顶空平衡时间和平衡温度,并进行了加标回收实验。在相应的浓度范围内线性关系良好,r=0.9996,环氧乙烷*低检出限为0.02μg/mL,当称样量为1.0g,定容体积为5mL时,检出限为0.1μg/g。方法可以满足标准要求,对口罩和防护服中环氧乙烷残留量检测具有重要意义。

Chromosorb 101  HP 60～80目；玻璃柱长2m*3 mm
During the novel coronavirus pneumonia epidemic, in order to speed up the listing of masks and shorten the analysis time of ethylene oxide. Methods 10 batches of medical surgical masks sterilized by ethylene oxide at normal sterilization concentration without any analysis treatment were randomly selected as Samples, using gas chromatograph as the detection method, remove the sample packaging, place the sample on the ultra-clean workbench, and detect the residual amount of ethylene oxide at different analysis times under the condition of the maximum wind speed of vertical flow, and analyze the detection results. Results Conclusion By increasing the circulation speed of the ambient air, the ethylene oxide contained in the mask can be quickly resolved to meet the standard requirements, so as to reasonably avoid the analysis time before the sterility test, shorten the factory inspection period, and speed up the listing of the mask.


Haohan Chromatography (Shandong) Application Technology Development Co., Ltd. has established an analytical method for the determination of ethylene oxide residues in masks and protective clothing by headspace-gas chromatography. The determination method and conditions were optimized through experiments, the column type, headspace equilibrium time and equilibrium temperature were determined, and standard addition and recovery experiments were carried out. The linear relationship is good in the corresponding concentration range, r=0.9996, the minimum detection limit of ethylene oxide is 0.02μg/mL, when the weighing sample is 1.0g and the constant volume is 5mL, the detection limit is 0.1μg /g. The method can meet the standard requirements and is of great significance for the detection of ethylene oxide residues in masks and protective clothing.

Chromosorb 101 HP 60～80 mesh; glass column length 2m*3 mm